We can work on Protocol Development

  1. Do you think the background information provided in each of the two protocols is sufficient to support the
    investigator’s claim? (2-3 paragraphs)
  2. Note the differences in study populations for each protocol. What are the things you may need to consider in
    protocol 1 versus protocol 2? (2-3 paragraphs)
  3. Please list at least 3 study limitations/potential risks for each protocol. Which study risk do you think poses a
    greater risk. Explain why? (3-4 paragraphs)
    4.If you were a grant awarder, which protocol would you likely fund and why? Provide a thorough assessment

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vidual. Ultimately this is done with the intent of rationalising his experience. [xxxxxxx] Although Humbert gains some integration, even in his own psyche, the centrality he establishes at the beginning crumples as he grows more obsessive, thus falling into the trap of madness due to his existence in isolation – I am ready to yank you out of Beardsley and lock you up you know where, but this must stop. I am ready to take you away the same time it takes to pack a suitcase. Humbert’s forceful, almost violent language emphasises the power dynamic: there is, by very virtue of its nature, a lack of equality in the relationship. However, linguistically this is reinforced, meaning that it continuously pivots around Humbert’s needs, belying the presence of megalomania in his behaviour. Lolita’s escape therefore results in a scene, as can be gathered from her name being the title, to actively fantasise and abuse her distorts Humbert’s ability, thus effectively distorting his “Humberland” and forcing him into his “new solitude”. Lolita leaves him on 4th of July Independence Day Defiled lolita like defiling america ‘And I catch myself thinking today that our long journey had only defiled with a sinuous trail of slime the lovely, trustful, dreamy, enormous country that by then, in retrospect, was no more to us than a collection of dog-eared maps, ruined tour books, old tires, and her sobs in the night – every night, every night – the moment I feigned sleep.’ (175-176)>

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