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Do you think Breakthrough Therapy Designations for drugs offer unique benefits for patients? Expedited availability is typically to meet an unmet medical need, what in your opinion is the greatest risk associated with such designations? What are their safety pros and cons?

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RCD Ministerial Council meeting held in Pakistan in January 1976 the three member states resolved to take measures to strengthen and revitalize the RCD. This clearly reflected an awareness that the organization had not been able to achieve all that it set out to achieve. At the Izmir RCD Summit held in April 1976, the then Pakistani Premier emphasized the importance of removing all obstacles between the intra-regional trade of these two nations to establish a free trade area. The Izmir Treaty was signed in March 1977 by RCD member nations, which paved the way for the foundation of RCD investment and development bank to initiate, promote and finance projects of a regional importance (Ali, 2001). As a member of RCD Pakistan and Turkey made a good progress like various roads for enlarged Pakistan-Turkish trade were explored, it was originate that Turkish traders were interested in importing from Pakistani items that like surgical instruments, caustic soda, glycerin, castor oil, and products of stainless steel. On the other side Pakistani Importers were keen to buy chemicals and textiles auxiliaries among other goods from Turkey. At the session of the Pakistan-Turkish Joint Commission for Economic and Technical Cooperation which was held in Islamabad (Pakistan) in March 1977, the two governments Pakistan and Turkey obligated to identify a number of areas of cooperation, counting agriculture and food. That interest was shown at the time of launching joint ventures in the fields of commerce, industr>

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