What are the intensities of statins and when is each indicated (and why does simvastatin 80mg not appear in the new guidance)? • Example: what intensity statin should a diabetic be on ? • Example:
what intensity ststain should a patient with clinical ASCVD be on • Example: what if my 10 year risk was 6% or 22 % -What type of monitoring is indicated? Consider especially LFTs and CK! -how are
side effects managed (eg muscle pain with statins)? • See 2013 ACC/AHA Guideline on the Treatment of Blood Cholesterol to Reduce Atherosclerotic Cardiovascular Risk in Adults recommendations -what
do the 2013 guidelines say about add on therapies (fibrates, absorption inhibitors, etc) -The text address other guidelines such as 2004 ATPIII guidance which does advocate add on therapies for
additional LDL lowering. What “other” cholesterol medications are there (eg Niacin to increase HDL, fibrates for TGs) and how are they monitored and side effects managed (if at all)?